MOTS-C

MOTS-C peptide: a mitochondrial-derived research compound in Australia and New Zealand

MOTS-C is a research peptide (a short string of amino acids, the small parts that build proteins). It is a mitochondrial-derived peptide (MDP), meaning its code sits inside the mitochondria, the cell’s energy parts that carry their own small set of DNA. Its formal name, the Mitochondrial Open Reading Frame of the 12S rRNA type-c, gives the short label MOTS-C. Neurogen Research offers MOTS-C across Australia and New Zealand as a freeze-dried (lyophilised) powder, strictly for in-vitro (test-tube and cell) laboratory research.

MOTS-C peptide: quick facts

• Compound: MOTS-C, a 16-amino-acid mitochondrial-derived peptide (MDP).
• Purity & testing: above 98% by HPLC (latest batch 98.1%), checked by the independent lab Janoshik, with a batch Certificate of Analysis.
• Form: white freeze-dried (lyophilised) powder in a sealed vial.
• Sizes: 10mg and 40mg vials, as single vials, with a starter kit, or in a 10x bulk pack.
• Delivery: same-day dispatch from Sydney before 12pm AEST, free express over $200.
• Research use: in-vitro laboratory research only (not for human or animal use).

What is MOTS-C, and where does its code come from?

MOTS-C is a single chain of 16 amino acids built to one set sequence, so it is fully synthetic and is not a steroid. Its stand-out feature is its origin: most peptides are coded by DNA in the cell nucleus, while MOTS-C is coded by mitochondrial DNA instead.

What researchers examine with MOTS-C in the lab

In cell-based experiments, researchers study MOTS-C’s mechanism (how it behaves at the cell level): how it relates to the AMPK pathway (AMPK, or AMP-activated protein kinase, is an enzyme that acts as a cell’s energy sensor) and how signs of mitochondrial activity change around it. This work is done in cells and tissue preparations, never in people or animals.

Is MOTS-C a medicine? Its regulatory status

No. The MOTS-C sold here is an investigational research compound, still under study and not approved as a product for use. It has no approval from the TGA (the Therapeutic Goods Administration, Australia’s medicines regulator) or the FDA for the use described here. It is not a medicine, supplement, cosmetic, or consumer product, and Neurogen Research provides it only as material for laboratory research.

MOTS-C among mitochondrial and longevity research compounds

On the Neurogen Research catalogue, MOTS-C is listed in the Metabolic Research range as a reference research chemical. As a mitochondrial peptide, it is often studied beside other cellular-energy compounds, notably SS-31, a peptide that targets the mitochondria directly, and NAD+, a coenzyme (a helper molecule) central to how cells make energy. These comparisons are in-vitro only.

Neurogen Research testing: MOTS-C purity and the CoA

Every batch of MOTS-C is tested by Janoshik, an independent third-party laboratory, before listing. Purity is measured by HPLC (high-performance liquid chromatography, which splits a sample so the share of the target compound can be read) and comes back above 98%, latest batch 98.1%. The batch Certificate of Analysis (CoA) is posted on the Neurogen Research certificates page for independent checking, so you can match a vial to its own figures before buying.

Buy MOTS-C peptide in Australia and New Zealand: sizes, bulk and delivery

• MOTS-C peptide for sale in Australia: buy online from Neurogen Research, an Australian supplier holding local stock.
• Choose a 10mg or 40mg vial on its own, or with a starter kit of basic reconstitution supplies.
• For larger projects, the 10x MOTS-C pack (ten vials) lowers the cost per vial.
• Orders before 12pm AEST ship the same business day from Sydney by tracked Australia Post Express.
• Metro delivery is usually 2 to 4 business days, regional 3 to 5, and New Zealand 4 to 6; express is free over $200 (flat $14.95 under that), and every order includes its batch CoA.

MOTS-C storage and reconstitution

• Keep sealed vials below 25°C short-term, or near -20°C (a normal freezer) for longer, out of direct light.
• To reconstitute (turn the powder back into a liquid for lab use), add sterile or bacteriostatic water (water with a preservative that slows bacterial growth).
• Refrigerate the mixed solution, use it within a few weeks, and keep freeze-thaw cycles to a minimum, since repeated freezing and thawing can break the peptide down.

MOTS-C specifications table

MOTS-C: common research questions

What is the MOTS-C peptide?

MOTS-C is a synthetic research peptide in the mitochondrial-derived peptide family, which means its code comes from mitochondrial DNA rather than the cell nucleus. It is a 16-amino-acid chain, supplied by Neurogen Research as a freeze-dried powder for in-vitro research.

What is MOTS-C used for in research?

In the laboratory, MOTS-C serves as a reference compound for studying cellular energy and mitochondrial activity, often set beside related compounds for comparison. Every part of this work is done in cell and tissue models, not in people or animals.

Is MOTS-C a peptide or a steroid?

It is a peptide, a chain of 16 amino acids built to a fixed sequence. It is not a steroid; the two are different kinds of molecule and are made in different ways.

How does MOTS-C work at the cell level?

Research looks at how MOTS-C relates to the AMPK pathway, the system a cell uses to sense and balance its energy, and how mitochondrial-activity markers shift around it. These are observations in cell models only (in-vitro), not effects measured in a living body.

How pure is Neurogen Research MOTS-C, and do I get a CoA?

The latest batch tested above 98% purity by HPLC, at 98.1%, through the independent lab Janoshik. Its Certificate of Analysis (CoA) is published on the Neurogen Research certificates page and travels with your order.

How is MOTS-C stored and prepared?

Keep sealed vials below 25°C for the short term, or near -20°C for longer. To prepare it, reconstitute with sterile or bacteriostatic water, refrigerate the solution, and avoid repeated freeze-thaw cycles.

Can I buy MOTS-C in Australia and New Zealand, and what sizes are there?

Yes. Neurogen Research sells MOTS-C online across Australia and New Zealand in 10mg and 40mg vials, as single vials, with a starter kit, or in a 10x bulk pack, shipped from Sydney.

Is MOTS-C approved for human or medical use?

No. MOTS-C is an investigational research compound and has not been approved by the TGA or FDA for the use sold here. It must not be used in humans or animals.

Disclaimer: Neurogen Research provides MOTS-C for in-vitro laboratory research only. It is not a medicine, supplement, or cosmetic, and it is not intended for human or animal use. By ordering, you confirm that you are a qualified researcher and will handle and use it in line with all applicable Australian and New Zealand laws.